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Search Results for " c2 factor "

Targets Recommended: FGFR PROTAC Linker

1

抑制剂 & 化合物

2

天然产物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T16486	Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD PF-05231023	FGFR; PROTAC Linker	Angiogenesis; PROTAC; Tyrosine Kinase/Adaptors
	Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 的合成分子。

化合物

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD

Cat.No: T16486

Synonym: PF-05231023

Target: FGFR, PROTAC Linker

Cat. No.	Product Name	Target	Signaling Pathways
T2873	Ginsenoside Rg2 Chikusetsusaponin I,Panaxoside Rg2,人参皂苷Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2,人参皂苷 Rg2	Beta Amyloid; GSK-3; NF-κB	Neuroscience; NF-κB; PI3K/Akt/mTOR signaling; Stem Cells
	Ginsenoside Rg2 (Chikusetsusaponin I) 是一种人参的主要活性成分。它能够降低Aβ1-42积聚，抑制脂多糖介导的VCAM-1和ICAM-1表达的增加。
T3830	20(R)-Ginsenoside Rg2 20R-Ginsenoside Rg2,20R-人参皂苷Rg2,20(R)-人参皂苷 Rg2	IL Receptor	Immunology/Inflammation
	20(R)-Ginsenoside Rg2 (20R-Ginsenoside Rg2) 是一种人参皂苷。它能够抑制肺癌 NCI-H1650 细胞，具有抗癌作用。

天然产物

Ginsenoside Rg2

Cat.No: T2873

Synonym: Chikusetsusaponin I,Panaxoside Rg2,人参皂苷Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2,人参皂苷 Rg2

Target: Beta Amyloid, GSK-3, NF-κB

20(R)-Ginsenoside Rg2

Cat.No: T3830

Synonym: 20R-Ginsenoside Rg2,20R-人参皂苷Rg2,20(R)-人参皂苷 Rg2

Target: IL Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01443	HChFc2 Protein, Mouse, Recombinant (His) C2 factor,HCF-2,Host cell factor ...	Mouse	E. coli
	Host cell factor 2(HCFC2) is a cytoplasmic protein. It contains 2 fibronectin type-III domains.HCFC2 binds KMT2A/MLL1, as component of the MLL1/MLL complex.Hcfc2 negative regulation of transcription from RNA polymerase II promoter.
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Vascular endothelial growth factor receptor 1,Vascu...	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPK-01268	Complement C2 Protein, Cynomolgus, Recombinant (His) C2,CO2,Complement C2,C3/C5 convertase,ARMD...	Cynomolgus	HEK293 Cells
	Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC.
TMPJ-00402	CD117 Protein, Human, Recombinant (hFc) KIT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...	Human	HEK293 Cells
	C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1/PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing sti...
TMPJ-01224	FGFRL1 Protein, Human, Recombinant (His) FGFR5,FGFR-5,FGFRL1,FGFR-Like Protein,FHFR,FGF Homologous	Human	HEK293 Cells
	Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly exp...
TMPY-01814	GASP-1/WFIKKN2 Protein, Human, Recombinant (His) WFIKKNRP,GASP-1,hGASP-1,WFDC20B,WAP, follistatin/ka...	Human	HEK293 Cells
	WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein, WFIKKN-related protein, WFIKKN2 and GASP1, is a secreted protein that belongs to the WFIKKN family. WFIKKN2 contains two BPTI/Kunitz inhibitor domains, one Ig-like C2-type (immunoglobulin-like) domain, one Kazal-like domain, one NTR domain and one WAP domain. WFIKKN2 ...
TMPJ-01166	IGFBP-7 Protein, Mouse, Recombinant (His) TAF,IGFBP-rP1,Insulin-like growth factor-binding pr...	Mouse	HEK293 Cells
	Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase inhibitor domain and a C-terminal immunoglobulin-like C2-type domain. Human and mouse IGFBP7 are highly homologous and share 94% aa sequence identity. It is expressed in many normal tissues and in cancer cells. It is abundantly expressed in high endothelial venules (HEVs) of bloo...

重组蛋白

HChFc2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01443

Species: Mouse

Expression System: E. coli

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00412

Species: Human

Expression System: HEK293 Cells

Complement C2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01268

Species: Cynomolgus

Expression System: HEK293 Cells

CD117 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00402

Species: Human

Expression System: HEK293 Cells

FGFRL1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01224

Species: Human

Expression System: HEK293 Cells

GASP-1/WFIKKN2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01814

Species: Human

Expression System: HEK293 Cells

IGFBP-7 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01166

Species: Mouse

Expression System: HEK293 Cells

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